HIGHLIGHTS
- who: Zhihong He from the Center for PancreaticSouth China University of have published the Article: KLF4 transcription factor in tumorigenesis, in the Journal: (JOURNAL) of 18/02/2023
SUMMARY
To exert transcriptional regulation, KLFs access to the nucleus via nuclear localization signal (NLS) sequences near or between zinc_fingers, and then bind to GC-rich DNA sites via the α-helix and β-folding of zinc_fingers structure. To fulfill these functions, KLFs proteins consist of three parts, the N-terminal domain, the C-terminal domain, and the repetitive amino_acids between the N-terminal and C-terminal . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.