Klk6 proteolysis is implicated in the turnover and uptake of

HIGHLIGHTS

  • who: Top from the Department of Pharmacy, School of Health Sciences, University of Patras, Rion-Patras, Athens, Greece have published the article: KLK6 proteolysis is implicated in the turnover and uptake of, in the Journal: (JOURNAL)
  • what: The authors show that recombinant and naturally secreted KLK6 can readily cleave α-synuclein fibrils that have the potential for cell-to-cell propagation in "a prion-like mechanism". Initially, the authors focused on the 192 N-termini of putatively secreted or membrane associated proteins that were present in both experiments. The authors show that proMMP2 is activated by . . .

     

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