Klotho gene de ciency causes salt-sensitive hypertension via monocyte chemotactic protein-1/cc chemokine receptor 2 – mediated in fl ammation

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  • who: Klotho Gene Deficiency Causes and collaborators from the Affiliated Hospital Medical University have published the Article: Klotho Gene De ciency Causes Salt-Sensitive Hypertension via Monocyte Chemotactic Protein-1/CC Chemokine Receptor 2 - Mediated In fl ammation, in the Journal: (JOURNAL)
  • what: This study investigated if KL deficiency affects BP and salt sensitivity using KL mutant heterozygous (+/2) mice and wild-type (WT) mice (9 weeks of age, 16 mice per group). This study showed, for the first time, that klotho deficiency increased salt sensitivity and elicited saltsensitive hypertension. This study showed that the . . .

     

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