Knock-down of ahcy and depletion of adenosine induces dna damage and cell cycle arrest

HIGHLIGHTS

• who: Lucija Beluamp#x0017E and iamp#x00107 from the (UNIVERSITY) have published the research: Knock-down of AHCY and depletion of adenosine induces DNA damage and cell cycle arrest, in the Journal: (JOURNAL) of 21/Dec/2017
• what: The authors show that reduced AHCY activity causes adenosine depletion with activation of the DNA damage response (DDR), leading to cell cycle arrest, a decreased proliferation rate and DNA damage. The aims of this study include the comparison of adenosine levels between AHCY-silenced and control samples and the evaluation of the connection between adenosine and the . . .
  

   

  

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