Knockdown of akr1c3 through inhibiting the phosphorylation of akt in hepatocellular carcinoma

HIGHLIGHTS

  • who: Jia Zheng et al. from the University, Tianjin, China, Department of Obstetrics and Gynecology, Tangshan Workers' Hospital, Tangshan, China have published the research work: Knockdown of AKR1C3 Through Inhibiting the Phosphorylation of AKT in Hepatocellular Carcinoma, in the Journal: (JOURNAL)
  • how: The statistical analysis was conducted in R. Cell proliferation was assayed by MTT cell colony-forming assay and wound healing assay. These results indicated that upregulation of AKR1C3 may be associated with sorafenib resistance in HCC patients and the development of HCC. In the experiment a dataset of patients with sorafenib treatment was . . .

     

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