Knockdown of mettl16 disrupts learning and memory by reducing the stability of mat2a mrna

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  • who: Runjiao Zhang from the DepartmentMedical University China have published the Article: Knockdown of METTL16 disrupts learning and memory by reducing the stability of MAT2A mRNA, in the Journal: (JOURNAL) of 18/06/2022
  • what: The results of the experiments described above suggest that MAT2A mRNA was stabilised if METTL16 was sufficient, which partially contributed to an increase in the abundance of mRNA. The authors focused on the roles and regulatory mechanisms of the m6A methyltransferase METTL16 in learning and memory as METTL16 and m6A levels were significantly upregulated in the hippocampi of MWM-trained . . .

     

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