HIGHLIGHTS
- who: Yang Gao from the (UNIVERSITY) have published the research work: Knockdown of RRM1 in tumor cells promotes radio-/chemotherapy induced ferroptosis by regulating p53 ubiquitination and p21-GPX4 signaling axis, in the Journal: (JOURNAL) of 26/Nov/2021
- how: To identify genes or pathways associated with RRM1 after radiation the authors conducted RNA sequencing analysis.
SUMMARY
Radiation resistance has yet to be fully elucidated. Cancer cells accumulate resistance to radiation by activating intrinsic mechanisms, such as DNA repair and apoptosis inhibition. Current studies show that the production of ROS and . . .
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