Knockdown of the long noncoding rna purpl induces apoptosis and sensitizes liver cancer cells to doxorubicin

HIGHLIGHTS

• who: Tsinat Berhane from the Center forAalborg University have published the Article: Knockdown of the long noncoding RNA PURPL induces apoptosis and sensitizes liver cancer cells to doxorubicin, in the Journal: Scientific Reports Scientific Reports
• what: The authors showed that PURPL is upregulated in both virus-unrelated HCC and in HCV-associated HCC compared to normal liver tissue, and that its expression correlates with p53 expression in the same tumor samples and is p53-dependent in liver cancer cell lines. This study has been approved by the Danish National Committee on Health Research Ethics (nr . . .
  

   

  

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