Knockout of katnal2 leads to autism-like behaviors and developmental delay in zebrafish

HIGHLIGHTS

  • who: Jing Zheng et al. from the Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China have published the Article: Knockout of Katnal2 Leads to Autism-like Behaviors and Developmental Delay in Zebrafish, in the Journal: (JOURNAL) of 26/07/2022
  • what: The authors generated a katnal2 loss-of-function allele in zebrafish using the CRISPR/Cas9 geneediting technology, revealed the morphological abnormity of katnal2-/- zebrafish at the early developmental stage, and characterized the behavioral changes of mutants both in larval stage and in adulthood. The authors propose that . . .

     

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