HIGHLIGHTS
- who: George Haddad et al. from the Renal Division, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO have published the research work: Knockout of the neonatal Fc receptor alters immune complex trafficking and lysosomal function in cultured podocytes, in the Journal: PLOS ONE of 29/01/2023
- what: The authors examine the role of FcRn in handling ICs in podocytes. The authors demonstrate that signaling pathways in cultured podocytes differ after treatment with IgG alone versus ICs and that podocyte proliferation in both WT and KO podocytes is suppressed by IC treatment . . .
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