Knowledge-graph-based cell-cell communication inference for spatially resolved transcriptomic data with spatalk

HIGHLIGHTS

  • who: Xin Shao from the (UNIVERSITY) have published the paper: Knowledge-graph-based cell-cell communication inference for spatially resolved transcriptomic data with SpaTalk, in the Journal: (JOURNAL) of 20/04/2022
  • what: For the inference of cell-cell communication, the authors demonstrate that SpaTalk enables the identification of known LRIs in space as shown in the cases based on the STARmap and Slide-seq mouse brain ST datasets (Supplementary Fig 2). Next, the authors focused on a region of interest (ROI) covering 42 spatial spots in space for in-depth exploration of TSK-stroma . . .

     

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