Korean red ginseng saponins play an anti-inflammatory role by targeting caspase-11 non-canonical inflammasomein macrophages

HIGHLIGHTS

  • who: Hui-Jin Cho et al. from the Department of Life Sciences, Kyonggi University, Suwon, Republic of Korea have published the article: Korean Red Ginseng Saponins Play an Anti-Inflammatory Role by Targeting Caspase-11 Non-Canonical Inflammasomein Macrophages, in the Journal: (JOURNAL)
  • what: This study explored the anti-inflammatory activity of the KRG saponin fraction (KRGSF) in caspase-11 inflammasome-activated macrophages. The authors demonstrated KRGSF-mediated anti-inflammatory effects both in_vitro and in_vivo by decreasing the activation of caspase-11 non-canonical inflammasome in macrophages and also explained a novel mechanism of KRGSF . . .

     

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