Kpna6 deficiency causes infertility in male mice by disrupting spermatogenesis

HIGHLIGHTS

• who: KEY WORDS Importin and collaborators from the The best-characterized mechanism of nuclear import involves karyopherin α and karyopherin β (also known as importin α and importin β)Karyopherin α proteins are composed of three main structural domains: an, terminal region, which is the karyopherin (importin) β binding (IBB) domain have published the research work: Kpna6 deficiency causes infertility in male mice by disrupting spermatogenesis, in the Journal: (JOURNAL) of 17/Nov/2020
• what: The authors show that ablation of Kpna6 in mice leads to infertility and has multiple cumulative effects on both germ cells and Sertoli cells.
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