Kras mutation variants and co-occurring pi3k pathway alterations impact survival for patients with pancreatic ductal adenocarcinomas

HIGHLIGHTS

• who: Adam C. Diehl and collaborators from the Division of Medical Oncology, Department of Medicine, University of Washington, Seattle, WA, USA have published the research work: KRAS Mutation Variants and Co-occurring PI3K Pathway Alterations Impact Survival for Patients with Pancreatic Ductal Adenocarcinomas, in the Journal: (JOURNAL)
• what: The authors report a greater incidence of co-occurring PI3K pathway alterations within this subgroup, which appears to offset some of their survival advantages.
• how: The authors examined incidence of mutation variants with and without co-occurring PI3K or other genomic alterations and evaluated association . . .
  

   

  

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