Krüppel-like factor 12 promotes colorectal cancer growth through early growth response protein 1

HIGHLIGHTS

  • who: Sun-Hee Kim et al. from the Departments Melanoma Medical Oncology, The University Texas MD Anderson Cancer Center have published the research: Krüppel-Like Factor 12 Promotes Colorectal Cancer Growth through Early Growth Response Protein 1, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0159899]. July 21, 2016 of /1371/
  • what: The authors show for the first time that KLF12 promotes CRC cell growth, at least in part by directly activating EGR1. The authors show that KLF12 and EGR1 levels synergistically correlate with poor prognosis in CRC.
  • how: The . . .

     

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