L-arginine ameliorates defective autophagy in gm2 gangliosidoses by mtor modulation

HIGHLIGHTS

• who: Beatriz Castejón-Vega and colleagues from the Research Laboratory, Oral Medicine Department, University of Sevilla, Sevilla, Spain have published the Article: L-Arginine Ameliorates Defective Autophagy in GM2 Gangliosidoses by mTOR Modulation, in the Journal: Cells 2021, 10, x FOR PEER REVIEW of 30/09/2021
• what: According to the study , the authors report that, when compared with healthy control cells, there is an enhanced expression of p62/SQSTM1 and build-up of autophagosomes, indicating impaired autophagic flux. The authors explore the cellular pathogenesis of GM2 gangliosidosis. The authors contend that the pathological . . .
  

   

  

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