L-asparaginase from penicillium sizovae produced by a recombinant komagataella phaffii strain

HIGHLIGHTS

• who: Marcela Freitas et al. from the Department of Biochemical and Pharmaceutical Technology, University of Sao Paulo have published the research work: L-Asparaginase from Penicillium sizovae Produced by a Recombinant Komagataella phaffii Strain, in the Journal: Pharmaceuticals 2022, 746 of 27/01/2019
• what: As the main reason for the interruption of L-asparaginase treatment is the development of hypersensitivity, caused partly by the protein`s high molecular weight and bacterial origin, an enzyme that leads to fewer side effects could be found in other microbial sources such as fungi, which are eukaryotic microorganisms . . .
  

   

  

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