L-carnitine attenuated hyperuricemia-associated left ventricular remodeling through ameliorating cardiomyocytic lipid deposition

HIGHLIGHTS

  • who: January and collaborators from the Nantong University, China have published the article: L-carnitine attenuated hyperuricemia-associated left ventricular remodeling through ameliorating cardiomyocytic lipid deposition, in the Journal: (JOURNAL)
  • what: The authors show the role of FA metabolism in HUA-associated LVR. This study showed that FA transport dysfunction plays is a critical mechanism in both cardiomyocytic injury and HUA-associated LVR and promoting cytoplasmic FA transportation into mitochondrion for metabolism through pharmacological treatment by LC is a valid strategy to attenuate HUA-associated LVR. This study provides a novel perspective to improve the . . .

     

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