L-kynurenine induces nk cell loss in gastric cancer microenvironment via promoting ferroptosis

HIGHLIGHTS

  • who: Jian-Xin Cui from the Department of General, The First Center, Chinese PLA General Hospital, Beijing, China (Army, Chongqing, China have published the paper: L-kynurenine induces NK cell loss in gastric cancer microenvironment via promoting ferroptosis, in the Journal: (JOURNAL)
  • what: The main reason for the low response rate in solid tumors is believed to be related with the immunosuppressive effects of the TME , however the mechanisms involved are still misty.
  • how: The authors conducted preliminary experiments to determine the effective concentration and safety of each inhibitor on NK cells. The . . .

     

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