Lack of fam20a, ectopic gingival mineralization and chondro/osteogenic modifications in enamel renal syndrome

HIGHLIGHTS

• who: Renata Kozyraki from the McGill University, Canada have published the paper: Lack of FAM20A, Ectopic Gingival Mineralization and Chondro/Osteogenic Modifications in Enamel Renal Syndrome, in the Journal: (JOURNAL)
• what: The authors focused on the gingival phenotype and studied the cellular and ultrastructural modifications associated with the absence of FAM20A.
• how: The results showed that proband`s gingival fibroblasts produced a matrix with a decreased mRNA ratio of COL1A1 to COL1A2 (0.8-fold lower by day 7 and 0.45-fold lower by day 21 Supplementary Figure 6) a condition prone . . .
  

   

  

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