Lactate-induced lactylation in skeletal muscle is associated with insulin resistance in humans

HIGHLIGHTS

  • who: August et al. from the King's College London, United Kingdom University of Massachusetts Boston have published the research: Lactate-induced lactylation in skeletal muscle is associated with insulin resistance in humans, in the Journal: (JOURNAL)
  • what: The aim of this study was to utilize both in_vivo and in_vitro experiments to determine if lactateinduced lactylation occurred in human skeletal muscle and whether this post-translational modification was associated with insulin resistance in humans. For the current study, a skeletal frontiersin.org 10.3389/fphys.2022.951390 cryopreserved for subsequent HSkMC experiments, as previously described . . .

     

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