HIGHLIGHTS
- who: Lucia Longhitano from the Department of Drug Sciences, University of Catania, Catania, Italy have published the research work: Lactate modulates microglia polarization via IGFBP6 expression and remodels tumor microenvironment in glioblastoma, in the Journal: (JOURNAL)
- what: The authors aimed at investigating the crosstalk between metabolism and in TME and GBM progression.
- how: The characterization of the GBM model is described in detail in Mayrhofer et_al . The results showed that lactate treatment induced a significant change in the expression of genes involved in mitochondrial biogenesis and oxidative_phosphorylation. The IGFBP6 gene_expression analysis obtained from . . .
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