Lactate oxidase/catalase-displaying nanoparticles efficiently consume lactate in the tumor microenvironment to effectively suppress tumor growth

HIGHLIGHTS

• who: Hyukjun Choi from the Department of Biological Sciences, National Institute of Science have published the Article: Lactate oxidase/catalase-displaying nanoparticles efficiently consume lactate in the tumor microenvironment to effectively suppress tumor growth, in the Journal: (JOURNAL)
• what: The approach described here would provide opportunities for developing new enzyme complex-based therapeutic tools to modulate the TME by controlling cancer metabolism.
• how: Live cell imaging capture results showed that while AaLS-ST- or AaLS/LOX/CAT-treated CT26 cells maintained their cell morphology and membrane integrity (Figs 4f h) AaLS/LOX-treated . . .
  

   

  

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