Lactational delivery of triclosan promotes non-alcoholic fatty liver disease in newborn mice

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  • who: Andru00e9 A. Weber from the pairs of, /, and Pparu03b1-null (Pparu03b1-/-) mice were obtained from Jackson Laboratory (Bar Harbor, ME), liver conditional knockout mice (Atf4u0394Hep) and control (Atf F/F) were obtained from Dr. Christopher M. Adams from the University of Iowa. The intestinal epithelial cell (IEC)-specific expression of the constitutively active gp, variant (gp Act) mice was produced previously58. All animals were housed at the University of California San Diego (UCSD) Animal Care Facility and received food and water ad libitum. Due to the tendency for TCS to accumulate in many animals and plants . . .

     

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