HIGHLIGHTS
SUMMARY
Hepatocellular carcinoma (HCC) is the sixth most common malignancy and the third cause of cancer-related death worldwide. The authors test the proficiency of human recombinant monomeric Ln332 γ2 in promoting HCC cell adhesion and migration, in comparison with human recombinant full-length Ln332, and gain insights into the activation status of the signaling mediators and effectors involved. According to these data, HCC cells mainly rely on Rac1 activity for adhesion, According to these data, HCC cells mainly rely on Rac1 activity for adhesion, whilewhile ERKs ERKs function serve to effective motility on γ2 . . .
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