HIGHLIGHTS
SUMMARY
Through a transporter with specificity for amino_acid analogs that possess cationic terminal guanidine groups, such as those contained in L-arginine. In another computer-based study, arginine was identified amongst the 20 amino_acids as the best inhibitor of the main protease in SARS-CoV-2. It was shown in another study that vitamin C inhibits SARS-CoV-2 3CLpro in_vitro. The results of this study showed that arginine has inhibitory activity against Mpro in_vitro. A vitamin C/arginine combination was found to have synergistic inhibitory activity in_vitro. Vitamin C and the amino_acid arginine have . . .
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