HIGHLIGHTS
- who: Jie Zhou et al. from the University of Waterloo, Canada have published the research work: Landmark mediation survival analysis using longitudinal surrogate, in the Journal: (JOURNAL)
- what: The authors compare mediation analysis for OS using longitudinal measures of tumor response versus conventional approaches using the single-valued objective response. The models comparing different measures are applied to two colorectal cancer studies in Section 2.4.
- how: This article presents a method for quantifying the treatment mediation effects of tumor response on survival using longitudinally observed tumor measurements.
SUMMARY
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