Lap1 supports nuclear adaptability during constrained melanoma cell migration and invasion

HIGHLIGHTS

• who: Yaiza Jung-Garcia from the (UNIVERSITY) have published the research work: LAP1 supports nuclear adaptability during constrained melanoma cell migration and invasion, in the Journal: (JOURNAL) of 23/08/2021
• what: The authors propose that LAP1 renders the nucleus highly adaptable and contributes to melanoma aggressiveness.
• how: As the degree of NE blebbing and migratory ability correlated with melanoma progression (Fig 1 and Extended Data Figs 1 and 3) the authors compared transcriptomes of A375M2 cells with A375P cells using gene set enrichment analysis (GSEA) and focusing on genes encoding nuclear proteins . . .
  

   

  

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