HIGHLIGHTS
SUMMARY
A previous study showed the advantage of a two-step imputation strategy in cattle, where step 1: impute a low-density (50k) SNP array marker set to a high-density (700k) SNP array marker set; and step 2: impute the imputed high-density marker set to WGS. Although the authors know that multi-breed reference could improve imputation accuracy, it is worth examining whether available high-density (HD) genotypes from crossbred pigs can be used as the intermediate reference panel for purebred pigs. Researches have used model species to study specific human diseases, e_g . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.