HIGHLIGHTS
- who: Jan T. Czerminski from the University of California, San Diego, United States have published the Article: Large-scale organoid study suggests effects of trisomy 21 on early fetal neurodevelopment are more subtle than variability between isogenic lines and experiments, in the Journal: (JOURNAL)
- how: After assessing three organoid generation protocols the authors chose to utilize a directed forebrain spheroid method to compare organoids generated from isogenic trisomic and disomic cell lines. The primary antibodies used in this study are provided in Table 2. The above results indicated that many more organoids should be examined . . .
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