HIGHLIGHTS
- who: Philip J.M. Brouwer from the Department Amsterdam University, AZ Amsterdam, the Netherlands have published the paper: Lassa virus glycoprotein nanoparticles elicit neutralizing antibody responses and protection, in the Journal: (JOURNAL) of December/14,/2022
- what: Inspection of the model showed that LAVA01 binds to a previously unknown neutralizing epitope comprising elements of GP1 and GP2 within a single protomer and can bind the GPC trimer at the maximum stoichiometry of 3.
SUMMARY
Each GPC protomer consists of two non-covalently bound subunits: the membrane-anchored GP2, which contains the . . .
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