Layout 1

HIGHLIGHTS

  • who: Doruk Emre and collaborators from the CNRS, Institut Jacques Monod, UMR7592, Université Paris Diderot, Paris , France have published the paper: Layout 1, in the Journal: (JOURNAL)
  • what: This work has revealed that Mad1 contributes to the proper functioning of mitosis, in addition to its role as the kinetochorebound receptor for Mad2.

SUMMARY

    In current models, a kinetochore-bound Mad1-Mad2 ‘core complex' catalyzes the formation of Mad2-Cdc20 complexes, which are an essential part of the anaphase inhibitor (De Antoni et_al, 2005; Mapelli et_al, 2007; Sironi et_al, 2002; Yang et_al . . .

     

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