Lcn2 secreted by tissue-infiltrating neutrophils induces the ferroptosis and wasting of adipose and muscle tissues in lung cancer cachexia

HIGHLIGHTS

• who: Dong Wang from the , week-old male C BL/, (Cat#, ), BALB/ cJGpt-Foxn1nu/Gpt mice (Cat#, ) were obtained from GemPharmatech (Nanjing, China have published the Article: LCN2 secreted by tissue-infiltrating neutrophils induces the ferroptosis and wasting of adipose and muscle tissues in lung cancer cachexia, in the Journal: (JOURNAL)
• what: The study provides new insights into how LCN2-induced functionally impacts tissue wasting.
• how: The authors showed that the chemical inhibition of ferroptosis inhibited tissue wasting in experimental models of lung cancer cachexia. Patient sample data were compared using the Wilcoxon . . .
  

   

  

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