Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic alzheimer’s disease

HIGHLIGHTS

• who: = Mini-Mental-State Examination and collaborators from the disease dementia (n=13)DELCODE is an ongoing prospective longitudinal study on the development of neuroimaging and biofluid-derived markers for the early detection of late onset sporadic Alzheimer`s disease. The study is conducted at eight University hospitals within the German Center for Neurodegenerative Diseases. Participants were defined as cognitively normal when showing a Clinical Dementia Rating of zero and neither reporting cognitive complaints nor scoring lower than, ., standard deviations (SD) of age-, sex-, and education-adjusted norms on all subtests of the German CERAD-NP Plus . . .
  

   

  

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