Left ventricle- and skeletal muscle-derived fibroblasts exhibit a differential inflammatory and metabolic responsiveness to interleukin-6

HIGHLIGHTS

  • who: Isabell Matz from the United Kingdom University of Oslo, Norway have published the paper: Left ventricle- and skeletal muscle-derived fibroblasts exhibit a differential inflammatory and metabolic responsiveness to interleukin-6, in the Journal: (JOURNAL)
  • what: In agreement, the authors show that LV- and SM-derived fibroblasts differ in their basal expression of ECM components and chemokines by which fibroblasts from the SM have a higher expression, except for basal LOXL2 expression, which is reduced compared to fibroblasts from the LV. The authors show that IL-6 stimulation increased the release of CCL7 to . . .

     

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