Leishmania donovani argininosuccinate synthase is an active enzyme associated with parasite pathogenesis

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  • who: Ines Lakhal-Naouar and collaborators from the Administration (FDA), Bethesda, Maryland, United States of America, Institute of Parasitology, McGill University and the Centre for Host-Parasite Interactions, Quebec have published the Article: Leishmania donovani Argininosuccinate Synthase Is an Active Enzyme Associated with Parasite Pathogenesis, in the Journal: (JOURNAL) of October/18,/2012
  • what: The authors demonstrate that though LdASS has a glycosomal targeting signal that binds the targeting apparatus in vitro only a small proportion of the total cellular ASS is localized in a vesicle as indicated by protection from protease digestion of the . . .

     

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