Leishmania infantum exoproducts inhibit human invariant nkt cell expansion and activation

HIGHLIGHTS

  • who: Maria Leite-de-Moraes and Anabela Cordeiro-da-Silva from the in Health (i S), Department of Medical Science, Aveiro University, Aveiro, Faculty of Pharmacy, Janeiro, Brazil have published the Article: Leishmania infantum Exoproducts Inhibit Human Invariant NKT Cell Expansion and Activation, in the Journal: (JOURNAL)
  • what: The authors provide evidence for a new mechanism of evasion, which causes inhibition of TCR-dependent expansion and activation of human iNKT_cells through release of exoproducts (Exo), EVs, and VDE by L infantum promastigotes. The authors propose that L infantum Exo, VDE, and EV fractions facilitate parasite . . .

     

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