Lens-specific βa3/a1-conditional knockout mice: phenotypic characteristics and calpain activation causing protein degradation and insolubilization

HIGHLIGHTS

• who: Roy Joseph and collaborators from the Department of Optometry and Vision Science, University of Alabama at Birmingham, Birmingham have published the article: Lens-specific u03b2A3/A1-conditional knockout mice: Phenotypic characteristics and calpain activation causing protein degradation and insolubilization, in the Journal: PLOS ONE of June/21,/2022
• what: The authors generated the u03b2A3/A1-crystallin mouse (named u03b2A3/A1ckO) and explored phenotypic changes and the function of the crystallin in the For a variety of reasons, u03b2A3/A1 crystallin is a unique protein for the some of the following reasons: (A) Besides beings . . .
  

   

  

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