Lentiviral vector mediated gene therapy for type i dent disease ameliorates dent disease-like phenotypes for three months in clc-5 null mice

HIGHLIGHTS

  • who: Manish Kumar Yadav from the Forest Institute Forest University of Medicine, Technology Way, Winston-Salem, NC, USA have published the Article: Lentiviral vector mediated gene therapy for type I Dent disease ameliorates Dent disease-like phenotypes for three months in ClC-5 null mice, in the Journal: (JOURNAL) of 27/Dec/2022
  • what: The authors report the generation of a ClC-5 null model by CRISPR-Cas9mediated gene mutation, followed by LV-mediated DD1 gene therapy in ClC-5 null mice. 27 December 2022 Thus, all mutant male mice used in the study were . . .

     

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