Levels of active tyrosine kinase receptor determine the tumor response to zalypsis

HIGHLIGHTS

  • who: Zalypsis et al. from the (UNIVERSITY) have published the paper: Levels of active tyrosine kinase receptor determine the tumor response to Zalypsis, in the Journal: (JOURNAL)
  • what: The aim of this study was to identify biomarkers defining the molecular basis of sensitivity/resistance to Zalypsis to assist in its clinical development. The authors propose the use of a specific tyrosine kinase inhibitor according to the RTK active in the patient's tumor, thus promoting personalized treatment.

SUMMARY

    Treatment of cells lines with Zalypsis leads to cell cycle delay in S . . .

     

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