Leveraging a powerful allogeneic dendritic cell line towards neoantigen-based cancer vaccines

HIGHLIGHTS

  • who: Plumas, and RD, from the PDC*line Pharma, Grenoble, France have published the research work: Leveraging a powerful allogeneic dendritic cell line towards neoantigen-based cancer vaccines, in the Journal: (JOURNAL)
  • what: NeoAgs appear attractive candidates to induce specific anti-tumor responses in cancer patients, on top of classical tumor-associated antigens and in association with ICIs.

SUMMARY

    Combination of ICIs with therapeutic cancer vaccines that aimed at priming or enhancing anti-tumor CD8+ T-cell effectors could increase the efficacy of each treatment used separately. Neoantigens as a source . . .

     

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