Leveraging an advanced simulated moving bed approach to achieve 3-component separation for enhanced impurity removal in a non-affinity cation exchange capture step

HIGHLIGHTS

• who: Serene W. Chen et al. from the RandD Center, R and D and Engineering, Organo Corporation, Koto City, Japan University, UNITED STATES have published the paper: Leveraging an advanced simulated moving bed approach to achieve 3-component separation for enhanced impurity removal in a non-affinity cation exchange capture step, in the Journal: PLOS ONE of 27/08/2022
• what: As a proof-of-concept the authors demonstrate the enhanced removal of strongly bound host cell proteins (HCP) from the target monoclonal antibody (mAb) through the utilisation of the advanced SMB approach in a . . .
  

   

  

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