Leveraging patient derived models of fgfr2 fusion positive intrahepatic cholangiocarcinoma to identify synergistic therapies

HIGHLIGHTS

• who: Michael E. Lidsky from the Published in partnership with The Hormel Institute, University of Minnesota have published the Article: Leveraging patient derived models of FGFR2 fusion positive intrahepatic cholangiocarcinoma to identify synergistic therapies, in the Journal: (JOURNAL) of March/01,/2021
• what: The authors report the generation and genomic characterization of patient-derived models of FGFR2 fusion-positive ICC, including a cell line, organoid, and xenograft. The authors show the effectiveness of this FGFR/HDAC combination extends to other FGFR fusionpositive solid tumors. The authors demonstrate the utility of these models to test therapeutic . . .
  

   

  

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