Lfa-1 and icam-1 expression induced during melanoma-endothelial cell co-culture favors the transendothelial migration of melanoma cell lines in vitro

HIGHLIGHTS

  • who: Melanoma et al. from the (UNIVERSITY) have published the research work: LFA-1 and ICAM-1 expression induced during melanoma-endothelial cell co-culture favors the transendothelial migration of melanoma cell lines in vitro, in the Journal: (JOURNAL) of 23/01/2012
  • what: The authors show here that HUVEC-conditioned medium induce cell-surface expression of LFA-1 on cell lines. The authors propose that transendothelial migration of melanoma would be a cooperating endeavor, with clumps favoring the binding to endothelial cells via the presence of LFA-1 on melanoma cells. The authors provide . . .

     

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