HIGHLIGHTS
- who: Alejandro Ramí from the Cordeliers (CRC) (INSERM), France University of Alabama at Birmingham have published the research: Ligand-based CAR-T cell: Different strategies to drive T cells in future new treatments, in the Journal: (JOURNAL)
SUMMARY
The aim of these therapies is focused on driving T-cell cytotoxicity specifically Frontiers in Immunology frontiersin.org 10.3389/fimmu.2022.932559 Autologous T_cells expressing CAR molecules are activated upon non-HLA-restricted ligand recognition, subsequent posttranslational phosphorylation of CD3z is produced, and the zeta-chain-associated protein kinase 70 (Zap-70) is . . .
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