Ligand-based chemoinformatic discovery of a novel small

HIGHLIGHTS

  • who: Top from the Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy have published the Article: Ligand-based chemoinformatic discovery of a novel small, in the Journal: (JOURNAL)
  • what: The authors described the use of chemoinformatic and virtual screening (VS) approaches against the full ZINC drug-like subset and the NCI (National Cancer Institute) lead-like set to potentially identify more active analogs of the lead compound NSC 119915 and to expand the understanding of structure-activity relationships (SARs).
  • how: The data showed that compound 7 was . . .

     

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