Ligustilide improves cognitive impairment via regulating the sirt1/ire1 α /xbp1s/chop pathway in vascular dementia rats

HIGHLIGHTS

  • who: Dong Peng et al. from the Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China have published the research work: Ligustilide Improves Cognitive Impairment via Regulating the SIRT1/IRE1 α /XBP1s/CHOP Pathway in Vascular Dementia Rats, in the Journal: Oxidative Medicine and Cellular Longevity 1.5 of 16/08/2022
  • what: The study showed that LIG increased the expression of Bcl2 and reduced the expression of Bax.
  • how: In this study an in_vivo model of bilateral common carotid artery occlusion and in_vitro model of oxygen glucose . . .

     

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