Lim kinases, promising but reluctant therapeutic targets: chemistry and preclinical validation in vivo

HIGHLIGHTS

  • who: Rayan Berabez and collaborators from the Institut de Chimie Organique et Analytique, University of OrlĂ©ans, CNRS UMR, have published the paper: LIM Kinases, Promising but Reluctant Therapeutic Targets: Chemistry and Preclinical Validation In Vivo, in the Journal: Cells 2022, 2090 of 13/06/2022
  • what: Throughout this review, we have seen that LIM kinases are indeed promising but reluctant therapeutic targets.
  • how: To further To differentiate between the active the active compounds they were tested for their inhibition of cofilin phosphorylation in compounds they were tested for their inhibition of cofilin . . .

     

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