Limited cross-variant neutralization after primary omicron infection: consideration for a variant-containing booster

HIGHLIGHTS

  • who: Harold Marcotte from the Department have published the paper: Limited cross-variant neutralization after primary Omicron infection: consideration for a variant-containing booster, in the Journal: (JOURNAL) of 21/07/2022

SUMMARY

    Received They found that BA. Omicron breakthrough infections mainly reactivate WT-induced memory B cells, reducing the diversity of antibodies, and possibly facilitating the emergence of new mutants. Omicron may thus evolve to escape the humoral immunity induced by BA.1 infection, suggesting that BA.1-derived vaccine boosters may not protect against new Omicron subvariants. Development of bivalent, or . . .

     

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