Lineage tracking to reveal the fate of hematopoietic stem cells influenced by flk2− multipotent progenitors after transplantation

HIGHLIGHTS

• who: Zheng Wang from the Mice All donor and recipient mice were, weeks old at the time of transplantationC BL6/J mice (CD45.2+, Jackson Laboratory, stock #00664) were the recipient mice. Donor HSCs were derived from C BL6/J mice (CD45.1+, Jackson Laboratory, stock #002014). , mice (CD45.1+/CD45.2+) derived from the cross of the two aforementioned mouse strains were used to isolate donor MPPs that were cotransplanted with HSCs. In a replicated experiment (Supplementary Fig., ), (CD45.1+/ CD45.2+) mice were donors for HSCs, and C BL6/J (CD45.1+) mice were donors . . .
  

   

  

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